PD Dr. med. Stefan Alig
Universitätsmedizin Essen
Klinik für Hämatologie & Stammzelltransplantation
Hufelandstraße 55
45147 Essen
45147 Essen
+49 201-723-5961
stefan.alig@uk-essen.deStudies
Aoki T, Duns G, Rai S, Jiang A, Lytle A, Yin Y, Kishida M, Yu Li M, Lee C, Smorra D, Hilton LK, Healy S, Alig SK, Shahrokh Esfahani M, Sarkozy C, Hung SS, Milne K, Telenius A, O Brien L, Wong JC, Cassidy C, Fujisawa M, Strong C, Goodyear T, Di Vito C, Luksik C, Edin G, Gonzalez L, Rangel Patiño J, Hong M, Wu S, Lee E, Sakhdari A, Takata K, Miyata-Takata T, Boyle M, Ben-Neriah S, Weng AP, Xu A, Merchant A, Roth A, Crump M, Kuruvilla J, Prica A, Kridel R, Huntsman DG, Nelson BH, Farinha P, Morin RD, Alizadeh AA, Savage KJ, Scott DW, Steidl C. Multidimensional Characterization of Tumor-Immune Architecture Reveals Clinically Relevant Classic Hodgkin Lymphoma Subtypes. Cancer Discov. 2026 Jan 30;. doi: 10.1158/2159-8290.CD-25-0859. [Epub ahead of print] PubMed PMID: 41615883.
Shi WY, Liu KJ, Esfahani MS, Mach KE, Phillips NA, Almanza D, Bajpai RK, Schroers-Martin JG, Trabanino L, Lee TJ, La V, Rodriguez G, Holton G, Chen SB, Mullane P, Wu DJ, Nesselbush MC, Sugio T, Cheng JC, Jabara I, Hamilton EG, Alig SK, Liu CL, Peterson DJ, Prado K, Shkolyar E, Thong A, Shah JB, Gill H, Kunder CA, Chan E, Khaki AR, Skinner EC, Alizadeh AA, Liao JC, Diehn M. Field-effect-informed urine liquid biopsy for bladder cancer. Cell. 2026 Feb 19;189(4):1024-1038.e9. doi: 10.1016/j.cell.2025.12.054. Epub 2026 Jan 27. PubMed PMID: 41605210; PubMed Central PMCID: PMC12962748.
Zamrik T, von Tresckow B, Alig SK. Circulating Tumor DNA Assessment in Classic Hodgkin Lymphoma: Ready for Primetime?. Hematol Oncol Clin North Am. 2026 Apr;40(2):165-177. doi: 10.1016/j.hoc.2025.12.001. Epub 2026 Jan 13. Review. PubMed PMID: 41535187.
Alig SK, Reinhardt HC, von Tresckow B. [What is established in the treatment of diffuse large B-cell lymphoma?]. Inn Med (Heidelb). 2025 Dec;66(12):1258-1266. doi: 10.1007/s00108-025-01999-x. Epub 2025 Oct 22. Review. PubMed PMID: 41125821.
Hamilton MP, Phillips N, Noordenbos T, Boegeholz J, Sugio T, Sworder BJ, Alig SK, Good Z, Schroers-Martin JG, Tamaresis J, Esfahani MS, Lu Y, Olsen M, Liu CL, Ehlinger Z, Desai M, Muffly L, Negrin RS, Arai S, Johnston L, Lowsky R, Meyer E, Rezvani A, Shizuru J, Weng WK, Shiraz P, Sidana S, Bharadwaj S, Smith M, Dahiya S, Sahaf B, Frank MJ, Mackall CL, Diehn M, Kurtz DM, Miklos DB, Alizadeh AA. CAR19 therapy drives expansion of clonal hematopoiesis and associated cytopenias. Res Sq. 2025 Oct 21;. doi: 10.21203/rs.3.rs-7746241/v1. PubMed PMID: 41282159; PubMed Central PMCID: PMC12633523.
Subramanian A, Su S, Flerlage J, Alig S, Younes S, Marks LJ, Pinnix C, Vega F, Steiner R, Kumar P, Mocikova H, Sykorova A, Prochazka V, Milito C, Allen P, Paulino D, Ramsay A, Flerlage T, Palese M, West R, Zhu C, Noordenbos T, Schroers-Martin J, Zhao S, Park NJ, Kalbasi A, Moding EJ, Newman AM, Advani RH, Hoppe RT, Diehn M, Natkunam Y, Alizadeh AA, Binkley MS. Distinct cell state ecosystems for nodular lymphocyte-predominant Hodgkin lymphoma. Nat Commun. 2025 Sep 26;16(1):8473. doi: 10.1038/s41467-025-63339-9. PubMed PMID: 41006203; PubMed Central PMCID: PMC12475200.
Roschewski M, Kurtz DM, Westin JR, Lynch RC, Gopal AK, Alig SK, Sworder BJ, Cherng HJ, Kuffer C, Blair D, Brown K, Goldstein JS, Schultz A, Close S, Chabon JJ, Diehn M, Wilson WH, Alizadeh AA. Remission Assessment by Circulating Tumor DNA in Large B-Cell Lymphoma. J Clin Oncol. 2025 Dec;43(34):3652-3661. doi: 10.1200/JCO-25-01534. Epub 2025 Aug 13. PubMed PMID: 40802906; PubMed Central PMCID: PMC12363663.
Strati P, Feng L, Westin JR, Nair R, Fayad LE, Rodriguez MA, Chihara D, Malpica L, Henderson J, Gallardo M, Rivera M, Wang I, Bolshakova A, Radko A, Kurtz D, Alig SK, Flowers CR, Alizadeh AA, Neelapu SS. Frontline acalabrutinib, lenalidomide and rituximab for advanced stage follicular lymphoma with high tumor burden: phase II trial. Nat Commun. 2025 Aug 7;16(1):7300. doi: 10.1038/s41467-025-62509-z. PubMed PMID: 40775236; PubMed Central PMCID: PMC12332063.
Kuehn JC, Neidert NN, Zhang J, Mutter J, Alig S, Klingler C, Hummel F, Ranganathan L, Bleul S, Beck J, Prinz M, Diehn M, Alizadeh A, Duyster J, Sankowski R, Heiland DH, Scherer F. The effect of ibrutinib on the myeloid cell compartment in CNS lymphoma. Leukemia. 2025 Jun;39(6):1532-1535. doi: 10.1038/s41375-025-02600-y. Epub 2025 Apr 10. PubMed PMID: 40210767; PubMed Central PMCID: PMC12133588.
Weinschenk S, Philipp U, Kuehn JC, Mueller K, Fauser J, Boeckle D, Gebhard I, Hinz M, Neidert N, Bleul S, Lauer EM, Mutter JA, Alig SK, Kurtz DM, Finke J, Marks R, Diehn M, Alizadeh AA, Reinacher PC, Wehrle J, Keller U, Wolf D, Kocher F, Chapuy B, Beck J, Prinz M, von Baumgarten L, Schorb E, Duyster J, Scherer F. Guiding clinical management of patients with CNS lymphomas by minimal-invasive detection of ctDNA in cerebrospinal fluid. Leukemia. 2025 May;39(5):1265-1268. doi: 10.1038/s41375-025-02583-w. Epub 2025 Apr 9. PubMed PMID: 40204895; PubMed Central PMCID: PMC12055572.
Alig SK, Chapuy B, Ennishi D, Dunleavy K, Hodson DJ. Evolving molecular classification of aggressive B-cell lymphoma. Histopathology. 2025 Jan;86(1):94-105. doi: 10.1111/his.15350. Epub 2024 Nov 15. Review. PubMed PMID: 39545339; PubMed Central PMCID: PMC11648360.
Alig SK. FISHing for clarity in double-hit lymphomas. Blood. 2024 Oct 10;144(15):1550-1552. doi: 10.1182/blood.2024026379. PubMed PMID: 39388163.
Khouja M, Jiang L, Pal K, Stewart PJ, Regmi B, Schwarz M, Klapper W, Alig SK, Darzentas N, Kluin-Nelemans HC, Hermine O, Dreyling M, Gonzalez de Castro D, Hoster E, Pott C, European Mantle Cell Lymphoma Network. Comprehensive genetic analysis by targeted sequencing identifies risk factors and predicts patient outcome in Mantle Cell Lymphoma: results from the EU-MCL network trials. Leukemia. 2024 Dec;38(12):2675-2684. doi: 10.1038/s41375-024-02375-8. Epub 2024 Sep 16. PubMed PMID: 39284897; PubMed Central PMCID: PMC11588657.
Alig S, Pott C, Chapuy B. [Malignant lymphomas - quo vadis? - What developments await us in diagnostics and therapy?]. Dtsch Med Wochenschr. 2024 May;149(11):638-645. doi: 10.1055/a-2160-5397. Epub 2024 May 15. PubMed PMID: 38749440.
Shukla ND, Schroers-Martin JG, Sworder BJ, Kathuria KR, Alig SK, Frank MJ, Miklos DB, Coutre S, Diehn M, Khodadoust MS, Roschewski M, Kurtz DM, Alizadeh AA. Specificity of immunoglobulin high-throughput sequencing minimal residual disease monitoring in non-Hodgkin lymphomas. Blood Adv. 2024 Feb 13;8(3):780-784. doi: 10.1182/bloodadvances.2023011997. PubMed PMID: 38147627; PubMed Central PMCID: PMC10847740.
Lauer EM, Riegler E, Mutter JA, Alig SK, Bleul S, Kuehn J, Ranganathan L, Klingler C, Demerath T, Würtemberger U, Rau A, Weiß J, Eisenblaetter M, Bamberg F, Prinz M, Finke J, Duyster J, Illerhaus G, Diehn M, Alizadeh AA, Schorb E, Reinacher PC, Scherer F. Improved early outcome prediction by MRI-based 3D tumor volume assessment in patients with CNS lymphomas. Neuro Oncol. 2024 Feb 2;26(2):374-386. doi: 10.1093/neuonc/noad177. PubMed PMID: 37713267; PubMed Central PMCID: PMC10836777.
Alig SK, Shahrokh Esfahani M, Garofalo A, Li MY, Rossi C, Flerlage T, Flerlage JE, Adams R, Binkley MS, Shukla N, Jin MC, Olsen M, Telenius A, Mutter JA, Schroers-Martin JG, Sworder BJ, Rai S, King DA, Schultz A, Bögeholz J, Su S, Kathuria KR, Liu CL, Kang X, Strohband MJ, Langfitt D, Pobre-Piza KF, Surman S, Tian F, Spina V, Tousseyn T, Buedts L, Hoppe R, Natkunam Y, Fornecker LM, Castellino SM, Advani R, Rossi D, Lynch R, Ghesquières H, Casasnovas O, Kurtz DM, Marks LJ, Link MP, André M, Vandenberghe P, Steidl C, Diehn M, Alizadeh AA. Distinct Hodgkin lymphoma subtypes defined by noninvasive genomic profiling. Nature. 2024 Jan;625(7996):778-787. doi: 10.1038/s41586-023-06903-x. Epub 2023 Dec 11. PubMed PMID: 38081297; PubMed Central PMCID: PMC11293530.
Johansson P, Alig S, Richter J, Hanoun C, Rekowski J, Dürig J, Ylstra B, de Jong D, Klapper W, Alizadeh AA, Dührsen U, Hüttmann A. Outcome prediction by interim positron emission tomography and IgM monoclonal gammopathy in diffuse large B-cell lymphoma. Ann Hematol. 2023 Dec;102(12):3445-3455. doi: 10.1007/s00277-023-05393-1. Epub 2023 Aug 11. PubMed PMID: 37566280; PubMed Central PMCID: PMC10640472.
Lynch RC, Ujjani CS, Poh C, Warren EH, Smith SD, Shadman M, Till B, Raghunathan VM, Alig S, Alizadeh AA, Gulhane A, Chen DL, Tseng Y, Coye H, Shelby M, Ottemiller S, Keo S, Verni K, Du H, Vandermeer J, Gaston A, Rasmussen H, Martin P, Marzbani E, Voutsinas J, Gopal AK. Concurrent pembrolizumab with AVD for untreated classic Hodgkin lymphoma. Blood. 2023 May 25;141(21):2576-2586. doi: 10.1182/blood.2022019254. PubMed PMID: 36913694; PubMed Central PMCID: PMC10273164.
Cherng HJ, Alig SK, Oki Y, Nastoupil LJ, Fayad L, Neelapu SS, Turturro F, Hagemeister F, Craig AFM, Macaulay CW, Rodriguez MA, Lee HJ, McDonnell TJ, Flowers CR, Vega F, Green MR, Feng L, Kurtz DM, Alizadeh AA, Davis RE, Westin JR. A phase 1/2 study of lenalidomide and obinutuzumab with CHOP for newly diagnosed DLBCL. Blood Adv. 2023 Apr 11;7(7):1137-1145. doi: 10.1182/bloodadvances.2022008174. PubMed PMID: 36375046; PubMed Central PMCID: PMC10111343.
Sworder BJ, Kurtz DM, Alig SK, Frank MJ, Shukla N, Garofalo A, Macaulay CW, Shahrokh Esfahani M, Olsen MN, Hamilton J, Hosoya H, Hamilton M, Spiegel JY, Baird JH, Sugio T, Carleton M, Craig AFM, Younes SF, Sahaf B, Sheybani ND, Schroers-Martin JG, Liu CL, Oak JS, Jin MC, Beygi S, Hüttmann A, Hanoun C, Dührsen U, Westin JR, Khodadoust MS, Natkunam Y, Majzner RG, Mackall CL, Diehn M, Miklos DB, Alizadeh AA. Determinants of resistance to engineered T cell therapies targeting CD19 in large B cell lymphomas. Cancer Cell. 2023 Jan 9;41(1):210-225.e5. doi: 10.1016/j.ccell.2022.12.005. Epub 2022 Dec 29. PubMed PMID: 36584673; PubMed Central PMCID: PMC10010070.
Mutter JA, Alig SK, Esfahani MS, Lauer EM, Mitschke J, Kurtz DM, Kühn J, Bleul S, Olsen M, Liu CL, Jin MC, Macaulay CW, Neidert N, Volk T, Eisenblaetter M, Rauer S, Heiland DH, Finke J, Duyster J, Wehrle J, Prinz M, Illerhaus G, Reinacher PC, Schorb E, Diehn M, Alizadeh AA, Scherer F. Circulating Tumor DNA Profiling for Detection, Risk Stratification, and Classification of Brain Lymphomas. J Clin Oncol. 2023 Mar 20;41(9):1684-1694. doi: 10.1200/JCO.22.00826. Epub 2022 Dec 21. PubMed PMID: 36542815; PubMed Central PMCID: PMC10419411.
Schroers-Martin JG, Alig S, Garofalo A, Tessoulin B, Sugio T, Alizadeh AA. Molecular Monitoring of Lymphomas. Annu Rev Pathol. 2023 Jan 24;18:149-180. doi: 10.1146/annurev-pathol-050520-044652. Epub 2022 Sep 21. Review. PubMed PMID: 36130071.
Esfahani MS, Hamilton EG, Mehrmohamadi M, Nabet BY, Alig SK, King DA, Steen CB, Macaulay CW, Schultz A, Nesselbush MC, Soo J, Schroers-Martin JG, Chen B, Binkley MS, Stehr H, Chabon JJ, Sworder BJ, Hui AB, Frank MJ, Moding EJ, Liu CL, Newman AM, Isbell JM, Rudin CM, Li BT, Kurtz DM, Diehn M, Alizadeh AA. Inferring gene expression from cell-free DNA fragmentation profiles. Nat Biotechnol. 2022 Apr;40(4):585-597. doi: 10.1038/s41587-022-01222-4. Epub 2022 Mar 31. PubMed PMID: 35361996; PubMed Central PMCID: PMC9337986.
Haebe S, Keay W, Alig S, Mohr AW, Martin LK, Heide M, Secci R, Krebs S, Blum H, Moosmann A, Louissaint A Jr, Weinstock DM, Thoene S, von Bergwelt-Baildon M, Ruland J, Bararia D, Weigert O. The molecular ontogeny of follicular lymphoma: gene mutations succeeding the BCL2 translocation define common precursor cells. Br J Haematol. 2022 Mar;196(6):1381-1387. doi: 10.1111/bjh.17990. Epub 2021 Dec 29. PubMed PMID: 34967008.
Kurtz DM, Soo J, Co Ting Keh L, Alig S, Chabon JJ, Sworder BJ, Schultz A, Jin MC, Scherer F, Garofalo A, Macaulay CW, Hamilton EG, Chen B, Olsen M, Schroers-Martin JG, Craig AFM, Moding EJ, Esfahani MS, Liu CL, Dührsen U, Hüttmann A, Casasnovas RO, Westin JR, Roschewski M, Wilson WH, Gaidano G, Rossi D, Diehn M, Alizadeh AA. Enhanced detection of minimal residual disease by targeted sequencing of phased variants in circulating tumor DNA. Nat Biotechnol. 2021 Dec;39(12):1537-1547. doi: 10.1038/s41587-021-00981-w. Epub 2021 Jul 22. PubMed PMID: 34294911; PubMed Central PMCID: PMC8678141.
Alig S, Macaulay CW, Kurtz DM, Dührsen U, Hüttmann A, Schmitz C, Jin MC, Sworder BJ, Garofalo A, Shahrokh Esfahani M, Nabet BY, Soo J, Scherer F, Craig AFM, Casasnovas O, Westin JR, Gaidano G, Rossi D, Roschewski M, Wilson WH, Meignan M, Diehn M, Alizadeh AA. Short Diagnosis-to-Treatment Interval Is Associated With Higher Circulating Tumor DNA Levels in Diffuse Large B-Cell Lymphoma. J Clin Oncol. 2021 Aug 10;39(23):2605-2616. doi: 10.1200/JCO.20.02573. Epub 2021 Apr 28. PubMed PMID: 33909455; PubMed Central PMCID: PMC8331064.
Sams L, Kruger S, Heinemann V, Bararia D, Haebe S, Alig S, Haas M, Zhang D, Westphalen CB, Ormanns S, Metzger P, Werner J, Weigert O, von Bergwelt-Baildon M, Rataj F, Kobold S, Boeck S. Alterations in regulatory T cells and immune checkpoint molecules in pancreatic cancer patients receiving FOLFIRINOX or gemcitabine plus nab-paclitaxel. Clin Transl Oncol. 2021 Nov;23(11):2394-2401. doi: 10.1007/s12094-021-02620-x. Epub 2021 Apr 19. PubMed PMID: 33876417; PubMed Central PMCID: PMC8455387.
Alig S, Jurinovic V, Shahrokh Esfahani M, Haebe S, Passerini V, Hellmuth JC, Gaitzsch E, Keay W, Tahiri N, Zoellner A, Rosenwald A, Klapper W, Stein H, Feller A, Ott G, Staiger AM, Horn H, Hansmann ML, Pott C, Unterhalt M, Schmidt C, Dreyling M, Alizadeh AA, Hiddemann W, Hoster E, Weigert O. Evaluating upfront high-dose consolidation after R-CHOP for follicular lymphoma by clinical and genetic risk models. Blood Adv. 2020 Sep 22;4(18):4451-4462. doi: 10.1182/bloodadvances.2020002546. PubMed PMID: 32941649; PubMed Central PMCID: PMC7509878.
Bararia D, Hildebrand JA, Stolz S, Haebe S, Alig S, Trevisani CP, Osorio-Barrios F, Bartoschek MD, Mentz M, Pastore A, Gaitzsch E, Heide M, Jurinovic V, Rautter K, Gunawardana J, Sabdia MB, Szczepanowski M, Richter J, Klapper W, Louissaint A Jr, Ludwig C, Bultmann S, Leonhardt H, Eustermann S, Hopfner KP, Hiddemann W, von Bergwelt-Baildon M, Steidl C, Kridel R, Tobin JWD, Gandhi MK, Weinstock DM, Schmidt-Supprian M, Sárosi MB, Rudelius M, Passerini V, Mautner J, Weigert O. Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma. Cell Rep. 2020 May 5;31(5):107522. doi: 10.1016/j.celrep.2020.107522. Epub 2020 Apr 23. PubMed PMID: 32330423.
Mondello P, Tadros S, Teater M, Fontan L, Chang AY, Jain N, Yang H, Singh S, Ying HY, Chu CS, Ma MCJ, Toska E, Alig S, Durant M, de Stanchina E, Ghosh S, Mottok A, Nastoupil L, Neelapu SS, Weigert O, Inghirami G, Baselga J, Younes A, Yee C, Dogan A, Scheinberg DA, Roeder RG, Melnick AM, Green MR. Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma. Cancer Discov. 2020 Mar;10(3):440-459. doi: 10.1158/2159-8290.CD-19-0116. Epub 2020 Jan 8. PubMed PMID: 31915197; PubMed Central PMCID: PMC7275250.
Alig S, Jurinovic V, Pastore A, Haebe S, Schmidt C, Zoellner AK, Dreyling M, Unterhalt M, Hoster E, Hiddemann W, Weigert O. Impact of age on clinical risk scores in follicular lymphoma. Blood Adv. 2019 Apr 9;3(7):1033-1038. doi: 10.1182/bloodadvances.2019032136. PubMed PMID: 30940638; PubMed Central PMCID: PMC6457218.
Hellmuth JC, Louissaint A Jr, Szczepanowski M, Haebe S, Pastore A, Alig S, Staiger AM, Hartmann S, Kridel R, Ducar MD, Koch P, Dreyling M, Hansmann ML, Ott G, Rosenwald A, Gascoyne RD, Weinstock DM, Hiddemann W, Klapper W, Weigert O. Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles. Blood. 2018 Oct 18;132(16):1695-1702. doi: 10.1182/blood-2018-03-837252. Epub 2018 Aug 20. PubMed PMID: 30126979.
Alig S, Jurinovic V, Pastore A, Bararia D, Häbe S, Hellmuth JC, Kridel R, Gascoyne R, Schmidt C, Zöllner AK, Buske C, Dreyling M, Unterhalt M, Hiddemann W, Hoster E, Weigert O. Impact of age on genetics and treatment efficacy in follicular lymphoma. Haematologica. 2018 Aug;103(8):e364-e367. doi: 10.3324/haematol.2018.187773. Epub 2018 Mar 15. PubMed PMID: 29545350; PubMed Central PMCID: PMC6068024.
Kunisch R, Guder P, Schinke K, Nörenberg D, Ruf VC, Alig S, Bauer HJ, Kirchner SK, Kruger S, Noerenberg D, Singer K, Tiedt S, Weckbach L, Wypior G, Angstwurm M. [Reforming the Surgical Section of the Practical Year at Ludwig-Maximilians-University Munich]. Zentralbl Chir. 2016 Jun;141(3):310-4. doi: 10.1055/s-0034-1396254. Epub 2015 Nov 10. PubMed PMID: 26554334.
Alig SK, Stampnik Y, Pircher J, Rotter R, Gaitzsch E, Ribeiro A, Wörnle M, Krötz F, Mannell H. The tyrosine phosphatase SHP-1 regulates hypoxia inducible factor-1α (HIF-1α) protein levels in endothelial cells under hypoxia. PLoS One. 2015;10(3):e0121113. doi: 10.1371/journal.pone.0121113. eCollection 2015. PubMed PMID: 25799543; PubMed Central PMCID: PMC4370726.
Alig SK, Dreyling M, Seppi B, Aulinger B, Witkowski L, Rieger CT. Severe cytokine release syndrome after the first dose of Brentuximab Vedotin in a patient with relapsed systemic anaplastic large cell lymphoma (sALCL): a case report and review of literature. Eur J Haematol. 2015 Jun;94(6):554-7. doi: 10.1111/ejh.12396. Epub 2014 Jul 2. Review. PubMed PMID: 24913471.
Koch E, Pircher J, Czermak T, Gaitzsch E, Alig S, Mannell H, Niemeyer M, Krötz F, Wörnle M. The endothelial tyrosine phosphatase SHP-1 plays an important role for vascular haemostasis in TNFα -induced inflammation in vivo. Mediators Inflamm. 2013;2013:279781. doi: 10.1155/2013/279781. Epub 2013 May 9. PubMed PMID: 23766558; PubMed Central PMCID: PMC3665258.
Pinilla S, Weckbach LT, Alig SK, Bauer H, Noerenberg D, Singer K, Tiedt S. Blogging medical students: a qualitative analysis. GMS Z Med Ausbild. 2013;30(1):Doc9. doi: 10.3205/zma000852. Epub 2013 Feb 21. PubMed PMID: 23467720; PubMed Central PMCID: PMC3589691.
Mannell HK, Pircher J, Chaudhry DI, Alig SK, Koch EG, Mettler R, Pohl U, Krötz F. ARNO regulates VEGF-dependent tissue responses by stabilizing endothelial VEGFR-2 surface expression. Cardiovasc Res. 2012 Jan 1;93(1):111-9. doi: 10.1093/cvr/cvr265. Epub 2011 Oct 13. PubMed PMID: 22002459.