Molecular Research – Cell Line Bank

  HBL-2 JVM-2 (71) SP-49/50B/- 53 (72) REC-1 (71) NECB-1 (30) GRANTA-519 (74,75) Mino (76) Z-138 (77) JEKO-1 (78)-1 M-1 (79) UPN-1 (33) UPN-2 (33) MAYER-1
Author Peng HW et al Melo JV et al Daibata M et al Melo JV et al Saltman DL et al Jadayel DM, Rudolph C et al Lai R et al Medeiros LJ et al Jeon HJ et al Goy A et al M'kacher R et a M'kacher R et a Zamo et al
Original diagnosis DLCL PLL ILL MCL Dcb/CcL MCL MCL Blastoid MCL MCL Blastoid MCL Blastoid MCL MCL MCL
Sample LN PB PB LN PB PB PB BM PB PB Pleural effusion Pleural effusion PB
Cyclin D1 overexpression ++ + + ++ + + + ++ + ++ ++ +  
CD5 - + -   + - + - + + + + +
CD23 + + +   + + - - - - - + -
EBV - + -/+/- - + + - - - + - - -
Ploidy 2N 2N 3N 2N- 4N- 2N- 3N+ 2N+ 3N- 2N+ 2N- 3N+ 2N
CC/M-FISH/SKY Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes
mCGH/aCGH Yes Yes Yes Yes Yes Yes   Yes Yes   Yes Yes  
P53 status Del/* wt/wt   wt/wt del/mu del/wt #/mut Wt/* del/mu   */mut del/mut del/mut
ATM status   wt/wt   Wt/* De/* del/mut     Ampl/*   #/polymorph #/mut Del/*
P16INKA4A status Del/* Wt/#   Hom del Wt Hom del   Del/* Del/*       Del/*
P16ink4a exp WB - + -   + - + - +       -
Other oncogenes           BCL-2 amp         C-MYC R BCL-2 amp C-MYC R C-MYC R
Druckversion (PDF) »
Fenster schließen »